THF production method
Industrial production begins with the use of aldose as a raw material, a mixture of aldose and vapor is introduced into a reactor filled with a zinc-chromium-manganese metal oxide (or palladium) catalyst, and the carbonyl group is removed at 400-420 ° C to form a furan; The framework nickel is used as a catalyst, and hydrogenation is carried out at 80-120 ° C to obtain tetrahydrofuran. The process produces 1 ton of tetrahydrofuran and consumes about 3 tons of polysaccharide aldehyde. There are many kinds of production methods developed later. The industrialization method has 1,4-butanediol catalytic dehydration ring method, because butanediol is made from acetylene and formaldehyde, this method is called Ray method (Reppe method); The 1,4-dichlorobutene, a by-product of the chloroprene monomer chloroprene, produces tetrahydrofuran, which is called the dichlorobutene method; a catalytic hydrogenation process using maleic anhydride as a raw material has been developed.